The evaluation of 5-amino- and 5-hydroxyuracil derivatives as potential quadruplex-forming agents-Reference-Cited by-同舟云学术

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The evaluation of 5-amino- and 5-hydroxyuracil derivatives as potential quadruplex-forming agents

Published:2017 Issue:10 Volume:15 Page:2174-2184
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Paragi Gábor¹²³⁴⁵,Kupihár Zoltán⁶⁷⁸⁹,Endre Gábor⁶⁷⁸⁹,Fonseca Guerra Célia¹²³⁴,Kovács Lajos⁶⁷⁸⁹^ORCID

Affiliation:

1. Department of Theoretical Chemistry and Amsterdam Center for Multiscale Modeling

2. Vrije Universiteit Amsterdam (VU)

3. 1081 HV Amsterdam

4. The Netherlands

5. MTA-SZTE Supramolecular and Nanostructured Materials Research Group

6. Department of Medicinal Chemistry

7. University of Szeged

8. 6720 Szeged

9. Hungary

Abstract

5-Hydroxyuracil has been identified as a building block for supramolecular quadruplex assemblies.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C6OB02574A

Reference82 articles.

1. S. Neidle and S.Balasubramanian, Quadruplex Nucleic Acids, The Royal Society of Chemistry, Cambridge, 2006

2. Kinetics of tetramolecular quadruplexes

3. E. Largy , J.-L.Mergny and V.Gabelica, in The Alkali Metal Ions: Their Role for Life, ed. A. Sigel, H. Sigel and O. R. K. Sigel, Springer International Publishing, Cham, 2016, pp. 203–258, 10.1007/978-3-319-21756-7_7

4. The role of alkali metal cations in the stabilization of guanine quadruplexes: why K+ is the best

5. 3-Substituted xanthines as promising candidates for quadruplex formation: computational, synthetic and analytical studies

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