A new strategy for improving cytotoxicity of a copper complex toward metastatic melanoma cells unveiled by EPR spectroscopy-Reference-Cited by-同舟云学术

A new strategy for improving cytotoxicity of a copper complex toward metastatic melanoma cells unveiled by EPR spectroscopy

Published:2023 Issue:14 Volume:13 Page:9715-9719
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Vieira Eduardo Guimarães¹²^ORCID,Fazzi Rodrigo Boni¹,Martins Daniel O. T. A.²^ORCID,Sheveleva Alena M.²,Tuna Floriana²^ORCID,da Costa Ferreira Ana Maria¹^ORCID

Affiliation:

1. Department of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, 05508-000 São Paulo-SP, Brazil

2. EPSRC National EPR Facility, Department of Chemistry and Photon Science Institute, University of Manchester, Manchester M13 9PL, UK

Abstract

An oxindolimine-copper(ii) complex with antitumor properties was immobilized in a silica matrix, and verified to be more active and selective due the formation of a dinuclear species, unveiled by continuous wave and pulsed EPR spectroscopy.

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

University of Manchester

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D2RA07266A

Reference24 articles.

1. Toward Multi-Targeted Platinum and Ruthenium Drugs—A New Paradigm in Cancer Drug Treatment Regimens?

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5. Synthesis, chemical characterization and cancer cell growth-inhibitory activities of Cu(ii) and Ru(iii) aliphatic and aromatic dithiocarbamato complexes