An engineered POSS drug delivery system for copper(<scp>ii</scp>) anticancer metallodrugs in a selective application toward melanoma cells-Reference-Cited by-同舟云学术

An engineered POSS drug delivery system for copper(ii) anticancer metallodrugs in a selective application toward melanoma cells

Published:2024 Issue:30 Volume:53 Page:12567-12581
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Vieira Eduardo Guimarães¹²^ORCID,de Paiva Raphael Enoque Ferraz¹^ORCID,Miguel Rodrigo Bernardi¹^ORCID,de Oliveira Ana Paula Araujo¹^ORCID,Franco de Melo Bagatelli Felipe³^ORCID,Oliveira Carla Columbano³^ORCID,Tuna Floriana²^ORCID,da Costa Ferreira Ana Maria¹^ORCID

Affiliation:

1. Departamento de Química Fundamental, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes 748, 05508-000 São Paulo, SP, Brazil

2. EPSRC National EPR Facility, Department of Chemistry and Photon Science Institute, University of Manchester, Oxford Road, M13 9PL, Manchester, UK

3. Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes 748, 05508-000 São Paulo, SP, Brazil

Abstract

Mononuclear oxindolimine-copper(ii) species, when inserted into a POSS matrix containing triazole groups, formed an additional binuclear species showing higher selectivity toward melanoma cells.

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/DT/D4DT00535J

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