A gold-catalyzed cycloisomerization/aerobic oxidation cascade strategy for 2-aryl indenones from 1,5-enynes-Reference-Cited by-同舟云学术

A gold-catalyzed cycloisomerization/aerobic oxidation cascade strategy for 2-aryl indenones from 1,5-enynes

Published:2018 Issue:47 Volume:16 Page:9147-9151
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Guo Jia¹²³⁴⁵,Peng Xiaoshi¹²³⁴⁵,Wang Xiaoyu¹²³⁴⁵,Xie Fukai¹²³⁴⁵,Zhang Xinhang¹²³⁴⁵,Liang Guoduan¹²³⁴⁵,Sun Zenghui¹²³⁴⁵,Liu Yongxiang¹²³⁴⁵^ORCID,Cheng Maosheng¹²³⁴⁵,Liu Yang¹²³⁴^ORCID

Affiliation:

1. Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

2. Ministry of Education

3. Shenyang 110016

4. P. R. China

5. Institute of Drug Research in Medicine Capital of China

Abstract

The syntheses of 2-aryl indenones via gold(i)-catalyzed cyclization/aerobic oxidation was reported. The mechanism was probed by heavy atom labelling and control experiments. A formal total synthesis of isoprekinamycin was achieved.

Funder

Natural Science Foundation of Liaoning Province

Foundation of Liaoning Province Education Administration

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB02582G

Reference45 articles.

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2. Diazo Group Electrophilicity in Kinamycins and Lomaiviticin A: Potential Insights into the Molecular Mechanism of Antibacterial and Antitumor Activity