A combined experimental and computational study of NHC-catalyzed allylation of allenoate with MBH esters: new regiospecific and stereoselective access to 1,5-enyne-Reference-Cited by-同舟云学术

A combined experimental and computational study of NHC-catalyzed allylation of allenoate with MBH esters: new regiospecific and stereoselective access to 1,5-enyne

Published:2022 Issue:1 Volume:9 Page:51-57
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Sun Fang¹,Lu Fangfang¹,Song Xue¹,Wu Wenchao¹,Zhang Kai¹,Yu Chenxia¹,Li Tuanjie¹,Wei Donghui²^ORCID,Yao Changsheng¹^ORCID

Affiliation:

1. Jiangsu Key Lab of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Materials Science, Jiangsu Normal University, Xuzhou, Jiangsu 221116, P R China

2. The College of Chemistry and Molecular Engineering, Zhengzhou University, 100 Science Avenue, Zhengzhou, Henan 450001, P R China

Abstract

An NHC-catalyzed regiospecific allylation of α-substituted allenoates with MBH carbonates derived from aryl aldehyde furnished highly functionalized 1,5-enynes.

Funder

National Natural Science Foundation of China

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D1QO01083B

Reference75 articles.

1. Intramolecular Cyclizations of Enynes Using RuClH(CO)(PPh3)3

2. Stereocontrolled Synthesis of Heteroannular Acetals from Functionalized 1,5-Enynes via Radical Cascades—Construction of Quaternary and 1,2-Diquaternary Centres in Polycyclic Systems