Pea protein-derived tripeptide LRW shows osteoblastic activity on MC3T3-E1 cells via the activation of the Akt/Runx2 pathway-Reference-Cited by-同舟云学术

Pea protein-derived tripeptide LRW shows osteoblastic activity on MC3T3-E1 cells via the activation of the Akt/Runx2 pathway

Published:2020 Issue:8 Volume:11 Page:7197-7207
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Arora Harshita¹²³⁴⁵,Shang Nan¹²³⁴⁵^ORCID,Bhullar Khushwant S.¹²³⁴⁵,Wu Jianping¹²³⁴⁵^ORCID

Affiliation:

1. Department of Agricultural

2. Food & Nutritional Science

3. University of Alberta

4. Edmonton

5. Canada

Abstract

Tripeptide LRW improves bone health by stimulating osteoblastic bone formation via the activation of the Akt/Runx2 signaling pathway as well as inhibiting osteoblast-mediated bone resorption via the RANK/RANKL/OPG system.

Funder

Natural Sciences and Engineering Research Council of Canada

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/FO/D0FO00497A

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