Electrostatic binding of polyanions using self-assembled multivalent (SAMul) ligand displays – structure–activity effects on DNA/heparin binding-Reference-Cited by-同舟云学术

Electrostatic binding of polyanions using self-assembled multivalent (SAMul) ligand displays – structure–activity effects on DNA/heparin binding

Published:2016 Issue:7 Volume:7 Page:4653-4659
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Fechner Loryn E.¹²³⁴,Albanyan Buthaina¹²³⁴,Vieira Vânia M. P.¹²³⁴,Laurini Erik⁵⁶⁷⁸⁹,Posocco Paola⁵⁶⁷⁸⁹^ORCID,Pricl Sabrina⁵⁶⁷⁸⁹^ORCID,Smith David K.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University of York

3. York

4. UK

5. Simulation Engineering (MOSE) Laboratory

6. Department of Engineering and Architectures (DEA)

7. University of Trieste

8. Trieste

9. Italy

Abstract

DNA and heparin, both highly charged polyanions, exhibit different binding preferences towards cationic ligands in nanoscale displays.

Funder

European Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/SC/C5SC04801J

Reference46 articles.

1. Polyanions and the Proteome

2. Cationic amphiphiles: promising carriers of genetic materials in gene therapy

3. Heparin sensing and binding – taking supramolecular chemistry towards clinical applications

4. Nanomedicine-Challenge and Perspectives

5. Combining supramolecular chemistry with biology

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