Nano-assembly of cytotoxic amides of moronic and morolic acid

Author:

Bildziukevich Uladzimir1,Šlouf Miroslav2ORCID,Rárová Lucie3,Šaman David4,Wimmer Zdeněk15ORCID

Affiliation:

1. Institute of Experimental Botany of the Czech Academy of Sciences, Isotope Laboratory, Vídeňská 1083, CZ-14220 Prague, Czech Republic

2. Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovský sq. 2, CZ-16206 Prague 6, Czech Republic

3. Palacký University, Faculty of Science, Department of Experimental Biology, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic

4. Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, CZ-16610 Prague, Czech Republic

5. University of Chemistry and Technology in Prague, Department of Chemistry of Natural Compounds, Technická 5, CZ-16628 Prague, Czech Republic

Abstract

Moronic acid and morolic acid, less frequently studied plant triterpenoids, were subjected to derivation with several structural modifiers, namely, piperazine-, pyrazine-, 1H-indole- and l-methionine-based compounds.

Funder

Ministerstvo Průmyslu a Obchodu

Technologická Agentura České Republiky

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

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