N-Heterocyclic carbene-catalyzed formal [3 + 3] annulation of alkynoic acid esters with indolin-3-ones: access to functionalized pyrano[3,2-b]indol-2-ones-Reference-Cited by-同舟云学术

N-Heterocyclic carbene-catalyzed formal [3 + 3] annulation of alkynoic acid esters with indolin-3-ones: access to functionalized pyrano[3,2-b]indol-2-ones

Published:2019 Issue:13 Volume:6 Page:2291-2295
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Sun Kewen¹²³⁴⁵,Jin Shiyi¹²³⁴⁵,Fang Shuaishuai¹²³⁴⁵,Ma Rui¹²³⁴⁵,Zhang Xinmiao¹²³⁴⁵,Gao Maoyu¹²³⁴⁵,Zhang Wanqi¹²³⁴⁵,Lu Tao¹²³⁴⁵,Du Ding¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Natural Medicines

2. Department of Organic Chemistry

3. China Pharmaceutical University

4. Nanjing

5. P. R. China

Abstract

The structurally interesting pyrano[3,2-b]indol-2-ones were synthesized by an N-heterocyclic carbene-catalyzed formal [3 + 3] annulation of alkynoic acid esters.

Funder

National Natural Science Foundation of China

Double First Class University Plan

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/QO/C9QO00468H

Reference41 articles.

1. NHC-Catalyzed Generation of α,β-Unsaturated Acylazoliums for the Enantioselective Synthesis of Heterocycles and Carbocycles

2. N-Heterocyclic Carbene Catalysis via the α,β-Unsaturated Acyl Azolium