Highly selective and rapidly activatable fluorogenic Thrombin sensors and application in human lung tissue-Reference-Cited by-同舟云学术

Highly selective and rapidly activatable fluorogenic Thrombin sensors and application in human lung tissue

Author:

Megia-Fernandez Alicia¹²³⁴⁵,Mills Bethany⁶⁷⁸³⁴,Michels Chesney⁶⁷⁸³⁴,Chankeshwara Sunay V.¹²³⁴⁵,Dhaliwal Kevin⁶⁷⁸³⁴,Bradley Mark¹²³⁴⁵^ORCID

Affiliation:

1. EaStChem

2. School of Chemistry

3. University of Edinburgh

4. Edinburgh

5. UK

6. EPSRC IRC Hub. Pulmonary Optical Molecular Imaging Group

7. MRC/Centre of Inflammation Research

8. Queen's Medical Research Institute

Abstract

A fast and selective fluorogenic probe for Thrombin is reported and applied in ex vivo fibrotic human lung tissue.

Funder

Seventh Framework Programme

Medical Research Council

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

Reference35 articles.

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