Optical molecular imaging of lysyl oxidase activity – detection of active fibrogenesis in human lung tissue
Author:
Affiliation:
1. School of Chemistry
2. EaStChem
3. University of Edinburgh
4. Edinburgh
5. UK
6. Pulmonary Optical Molecular Imaging Group
7. MRC/Centre of Inflammation Research
8. Queen's Medical Research Institute
Abstract
A fluorogenic probe provides real-time measurement of lysyl oxidase activity in ex vivo asinine and human lung tissue.
Funder
Medical Research Council
Engineering and Physical Sciences Research Council
European Union Seventh Framework Programme
Fundación Ramón Areces
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/SC/C5SC01258A
Reference52 articles.
1. Idiopathic Pulmonary Fibrosis: Prevailing and Evolving Hypotheses about Its Pathogenesis and Implications for Therapy
2. Mechanisms of fibrosis: therapeutic translation for fibrotic disease
3. ATS/ERS international multidisciplinary consensus classification of the idiopathic interstitial pneumonias
4. C. Mathers , T.Boerma and D. M.Fat, The global burden of disease: 2004 Update, 2008
5. Focus on collagen: in vitro systems to study fibrogenesis and antifibrosis _ state of the art
Cited by 26 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Pan-lysyl oxidase inhibition disrupts fibroinflammatory tumor stroma, rendering cholangiocarcinoma susceptible to chemotherapy;Hepatology Communications;2024-08
2. Lysyl Oxidases as Targets for Cancer Therapy and Diagnostic Imaging;ChemMedChem;2023-09-04
3. A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer;Nature Cancer;2023-08-28
4. The challenge of determining lysyl oxidase activity: Old methods and novel approaches;Analytical Biochemistry;2022-02
5. Early Detection Methods for Silicosis in Australia and Internationally: A Review of the Literature;International Journal of Environmental Research and Public Health;2021-07-31
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3