Asymmetric synthesis of polycyclic 3-fluoroalkylproline derivatives by intramolecular azomethine ylide cycloaddition-Reference-Cited by-同舟云学术

Asymmetric synthesis of polycyclic 3-fluoroalkylproline derivatives by intramolecular azomethine ylide cycloaddition

Published:2019 Issue:16 Volume:6 Page:2916-2923
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Rabasa-Alcañiz Fernando¹²³⁴,Hammerl Daniel¹²³⁴,Sánchez-Merino Anabel¹²³⁴,Tejero Tomás⁵⁶⁷⁴,Merino Pedro⁸⁶⁷⁴^ORCID,Fustero Santos¹²³⁴⁹^ORCID,del Pozo Carlos¹²³⁴^ORCID

Affiliation:

1. Departamento de Química Orgánica

2. Universidad de Valencia

3. E-46100 Burjassot

4. Spain

5. Instituto de Síntesis Química y Catálisis Homogénea (ISQCH)

6. Universidad de Zaragoza

7. 50009 Zaragoza

8. Instituto de Biocomputación y Fisica de Sistemas Complejos (BIFI)

9. Laboratorio de Moléculas Orgánicas

Abstract

The asymmetric intramolecular dipolar cycloaddition of azomethine ylides was developed for fluorinated dipolarophiles, being the RF group crucial for selectivity.

Funder

Ministerio de Economía y Competitividad

Gobierno de Aragón

Ministerio de Educación, Cultura y Deporte

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/QO/C9QO00525K

Reference72 articles.

1. Catalytic asymmetric construction of spiropyrrolidines via 1,3-dipolar cycloaddition of azomethine ylides