Identifying key barriers in cationic polymer gene delivery to human T cells
Author:
Affiliation:
1. Department of Bioengineering and Molecular Engineering and Sciences Institute
2. University of Washington
3. Seattle
4. USA
Abstract
Decreased uptake of polyplexes and an increased intracellular pH contribute to poor gene delivery to human T cellsviacationic polymers.
Funder
National Institute of Neurological Disorders and Stroke
National Cancer Institute
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering
Link
http://pubs.rsc.org/en/content/articlepdf/2019/BM/C8BM01262H
Reference45 articles.
1. Engineering Specificity and Function of Therapeutic Regulatory T Cells
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