High-Throughput <i>In Vivo</i> Screening Identifies Differential Influences on mRNA Lipid Nanoparticle Immune Cell Delivery by Administration Route-Reference-Cited by-同舟云学术

High-Throughput In Vivo Screening Identifies Differential Influences on mRNA Lipid Nanoparticle Immune Cell Delivery by Administration Route

Published:2024-06-11 Issue:25 Volume:18 Page:16151-16165
ISSN:1936-0851
Container-title:ACS Nano
language:en
Short-container-title:ACS Nano

Author:

Hamilton Alex G.¹^ORCID,Swingle Kelsey L.¹^ORCID,Thatte Ajay S.¹^ORCID,Mukalel Alvin J.¹,Safford Hannah C.¹^ORCID,Billingsley Margaret M.¹^ORCID,El-Mayta Rakan D.¹,Han Xuexiang¹,Nachod Benjamin E.¹,Joseph Ryann A.¹^ORCID,Metzloff Ann E.¹,Mitchell Michael J.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

2. Center for Precision Engineering for Health, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

3. Institute for RNA Innovation, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

4. Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

5. Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

Funder

National Center for Advancing Translational Sciences

National Science Foundation Graduate Research Fellowship Program

National Cancer Institute

American Cancer Society

Division of Chemical, Bioengineering, Environmental, and Transport Systems

Burroughs Wellcome Fund

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsnano.4c01171

Reference92 articles.

1. Gene delivery for immunoengineering

2. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

3. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine

4. A Vaccine against Ebola Virus

5. Viral Vectors for COVID-19 Vaccine Development

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Nano-Encapsulation and Conjugation Applied in the Development of Lipid Nanoparticles Delivering Nucleic Acid Materials to Enable Gene Therapies;Applied Nano;2024-08-29

2. Lipid Nanoparticles for Nucleic Acid Delivery Beyond the Liver;Human Gene Therapy;2024-08-28