Catalytic asymmetric direct aldol reaction of α-alkyl azlactones and aliphatic aldehydes
Author:
Affiliation:
1. Department of Chemistry
2. Brandeis University
3. Waltham
4. USA
Abstract
An unprecedented diastereoselective and enantioselective catalytic direct aldol reaction generating β-hydroxy-α-amino acid derivatives with alkyl-substituted adjacent quaternary-tertiary stereocenters.
Funder
National Institutes of Health
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/SC/C5SC02116B
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