Marine alkaloids as bioactive agents against protozoal neglected tropical diseases and malaria-Reference-Cited by-同舟云学术

Marine alkaloids as bioactive agents against protozoal neglected tropical diseases and malaria

Published:2021 Issue:12 Volume:38 Page:2214-2235
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Tempone Andre G.¹^ORCID,Pieper Pauline²,Borborema Samanta E. T.¹,Thevenard Fernanda³,Lago Joao Henrique G.³,Croft Simon L.⁴^ORCID,Anderson Edward A.²^ORCID

Affiliation:

1. Centre for Parasitology and Mycology, Instituto Adolfo Lutz, São Paulo, 01246-000, Brazil

2. Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK

3. Centre of Natural Sciences and Humanities, Federal University of ABC, Sao Paulo, 09210-580, Brazil

4. Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK

Abstract

This Review discusses the isolation and bioactivity of marine alkaloids against protozoan parasite diseases, and chemical syntheses that enable the further development of these scaffolds as drug leads.

Funder

FP7 People: Marie-Curie Actions

Fundação de Amparo à Pesquisa do Estado de São Paulo

Engineering and Physical Sciences Research Council

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NP/D0NP00078G

Reference140 articles.

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3. World Health Organization, https://www.who.int/news-room/fact-sheets/detail/chagas-disease-(american-trypanosomiasis) , accessed 18 February 2021

4. World Health Organization, https://www.who.int/news-room/fact-sheets/detail/trypanosomiasis-human-african-(sleeping-sickness) , accessed 18 February 2021

5. Neglected tropical diseases: progress towards addressing the chronic pandemic

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