Bifunctional phase-transfer catalysts for synthesis of 2-oxazolidinones from isocyanates and epoxides-Reference-Cited by-同舟云学术

Bifunctional phase-transfer catalysts for synthesis of 2-oxazolidinones from isocyanates and epoxides

Published:2020 Issue:21 Volume:10 Page:12360-12364
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Cui Dong-Xiao¹²³⁴⁵,Li Yue-Dan¹²³⁴⁵,Huang Ping¹²³⁴⁵,Tian Zhuang¹²³⁴⁵,Jia Yan-Yan⁶⁷⁸⁹⁵,Wang Ping-An¹²³⁴⁵^ORCID

Affiliation:

1. Department of Medicinal Chemistry

2. School of Pharmacy

3. The Fourth Military Medical University

4. Xi'an

5. P. R. China

6. Department of Pharmacy

7. Xijing Hospital

8. Fourth Military Medical University

9. Xi'an 710032

Abstract

A series of bifunctional phase-transfer catalysts were synthesized to catalyze the [3 + 2] coupling reaction of isocyanates and epoxides to afford 2-oxazolidinones in good to high yields (up to 92% yield) using PhCl as a solvent at 100 °C within 12 h.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA00693A

Reference32 articles.

1. An overview of the key routes to the best selling 5-membered ring heterocyclic pharmaceuticals

2. Factor Xa Inhibitors: Next-Generation Antithrombotic Agents

3. Potent Oxazolidinone Antibacterials with Heteroaromatic C-Ring Substructure