Total synthesis of aristolactam alkaloids via synergistic C–H bond activation and dehydro-Diels

Total synthesis of aristolactam alkaloids via synergistic C–H bond activation and dehydro-Diels–Alder reactions

Published:2017 Issue:5 Volume:8 Page:4130-4135
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Reddy Mallu Chenna¹²³⁴^ORCID,Jeganmohan Masilamani¹²³⁴¹^ORCID

Affiliation:

1. Department of Chemistry

2. Indian Institute of Science Education and Research

3. Pune 411021

4. India

Abstract

A concise total synthesis of aristolactam alkaloids by a synergistic combination of C–H bond activation and dehydro-Diels–Alder reactions is described.

Funder

Department of Science and Technology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C7SC00161D

Reference76 articles.

1. Naturally occurring aristolactams, aristolochic acids and dioxoaporphines and their biological activities

2. β-Phenylethylamines and the isoquinoline alkaloids

3. Naturally occurring aristolochic acid analogues and their toxicities

4. Synthesis of aristolactam analogues and evaluation of their antitumor activity

5. Aristolactams and 4,5-dioxoaporphines from Piper longum

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