Affiliation:
1. Jiangsu Key Laboratory of Function Control Technology for Advanced Materials School of Environmental and Chemical Engineering Jiangsu Ocean University Lianyungang 222005 Jiangsu China
2. Office of the Academic Affairs Jiangsu Ocean University Lianyungang 222005 Jiangsu China
Abstract
AbstractA Pd‐catalyzed formal [3+2] oxidative annulation of N‐aryl‐2‐aminopyridines and alkynes through pyridyl group directed C−H activation has been developed. This methodology provides a mild and atom‐economic approach for the efficient synthesis of highly substituted indoles in moderate to good yields, which features with mild reaction conditions, good functional group compatibility, operational simplicity and easy scale‐up.
Funder
Natural Science Foundation of Jiangsu Province