Structure determination, correction, and disproof of marine macrolide natural products by chemical synthesis
Author:
Affiliation:
1. Department of Applied Chemistry
2. Faculty of Science and Engineering
3. Chuo University
4. Tokyo 112-8551
5. Japan
Abstract
Integration of chemical synthesis, NMR spectroscopy, and various analytical means is key to success in the structure elucidation of stereochemically complex marine macrolide natural products.
Funder
Chuo University
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO00481F
Reference191 articles.
1. Peloruside A: a lead non-taxoid-site microtubule-stabilizing agent with potential activity against cancer, neurodegeneration, and autoimmune disease
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4. Bioactive Macrolides and Polyketides from Marine Dinoflagellates of the Genus Amphidinium
5. Amphidinolides, bioactive macrolides from symbiotic marine dinoflagellatesThe authors dedicate this review to the late Professor D. John Faulkner.
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