In vivo study and thermodynamic investigation of two lanthanum complexes, La(dpp)3 and La(XT), for the treatment of bone resorption disorders-Reference-Cited by-同舟云学术

In vivo study and thermodynamic investigation of two lanthanum complexes, La(dpp)3 and La(XT), for the treatment of bone resorption disorders

Published:2015 Issue:11 Volume:6 Page:6439-6447
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Cawthray J. F.¹²³⁴,Weekes D. M.⁵⁶⁷⁸⁴,Sivak O.⁹⁷⁸⁴,Creagh A. L.¹⁰⁷⁸⁴,Ibrahim F.¹¹¹²¹³,Iafrate M.⁵⁶⁷⁸⁴,Haynes C. A.¹⁰⁷⁸⁴,Wasan K. M.¹²³⁴,Orvig C.⁵⁶⁷⁸⁴

Affiliation:

1. College of Pharmacy and Nutrition

2. University of Saskatchewan

3. Saskatoon

4. Canada

5. Medicinal Inorganic Chemistry Group

6. Department of Chemistry

7. University of British Columbia

8. Vancouver

9. Faculty of Pharmaceutical Sciences

10. Michael Smith Laboratories and Department of Chemical and Biological Engineering

11. Pfizer Inc.

12. Groton

13. USA

Abstract

Lanthanum could act as a preventative measure against bone resorption disorders; two compounds are thoroughly investigated both in vivo and ex vivo as potential oral drug candidates.

Funder

Natural Sciences and Engineering Research Council of Canada

Canadian Institutes of Health Research

Canada Council for the Arts

Alexander von Humboldt-Stiftung

University of Canterbury

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/SC/C5SC01767J

Reference43 articles.

1. J. A. Kanis , Assessment of Osteoporosis at the Primary Health Care Level. Technical Report, 2007

2. An estimate of the worldwide prevalence and disability associated with osteoporotic fractures

3. FDA , Background Document for meeting of Advisory Committee for Reproductive Health Drugs and Drug Safety and Risk Management Advisory Committee, 9 September 2011

4. Bisphosphonates for Osteoporosis — Where Do We Go from Here?

5. Crystal Structure of Hydroxyapatite

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