Synthesis and mechanism of novel fluorescent coumarin–dihydropyrimidinone dyads obtained by the Biginelli multicomponent reaction

Author:

Vitório Felipe12345,Pereira Thiago Moreira12345,Castro Rosane Nora6457,Guedes Guilherme Pereira6457,Graebin Cedric Stephan12345,Kümmerle Arthur Eugen12345

Affiliation:

1. Laboratório de Diversidade Molecular e Química Medicinal (LaDMol-QM

2. Molecular Diversity and Medicinal Chemistry Laboratory)

3. Departament of Chemistry

4. Universidade Federal Rural do Rio de Janeiro

5. Rio de Janeiro

6. Programa de Pós-Gradução em Química (PPGQ)

7. Brazil

Abstract

Coumarin-β-ketoesters were used to synthesize new blue-fluorescent compounds exhibiting ICT. The Knoevenagel intermediate suggests that our Biginelli reaction passing by this mechanistic way is unlikely.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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