DIBI, a 3-hydroxypyridin-4-one chelator iron-binding polymer with enhanced antimicrobial activity-Reference-Cited by-同舟云学术

DIBI, a 3-hydroxypyridin-4-one chelator iron-binding polymer with enhanced antimicrobial activity

Published:2018 Issue:7 Volume:9 Page:1206-1212
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Ang M. Trisha C.¹²³⁴⁵,Gumbau-Brisa Roger¹²³⁴⁵,Allan David S.¹²³,McDonald Robert⁶⁴⁷⁸³^ORCID,Ferguson Michael J.⁶⁴⁷⁸³^ORCID,Holbein Bruce E.¹²³⁹¹⁰,Bierenstiel Matthias⁴⁵¹¹³^ORCID

Affiliation:

1. Chelation Partners Inc.

2. Halifax

3. Canada

4. Department of Chemistry

5. Cape Breton University

6. X-Ray Crystallography Laboratory

7. University of Alberta

8. Edmonton

9. Department of Microbiology and Immunology

10. Dalhousie University

11. Sydney

Abstract

Depriving microorganisms of bioavailable iron is a promising strategy for new anti-infective agents.

Funder

Natural Sciences and Engineering Research Council of Canada

National Research Council Canada

Atlantic Canada Opportunities Agency

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MD/C8MD00192H

Reference43 articles.

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2. What we may expect from novel antibacterial agents in the pipeline with respect to resistance and pharmacodynamic principles

3. Design, synthesis and antibacterial evaluation of a polycationic calix[4]arene derivative alone and in combination with antibiotics

4. Antibiotic resistance breakers: can repurposed drugs fill the antibiotic discovery void?

5. Iron Metabolism: A Promising Target for Antibacterial Strategies

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