Design, synthesis and antibacterial evaluation of a polycationic calix[4]arene derivative alone and in combination with antibiotics-Reference-Cited by-同舟云学术

Design, synthesis and antibacterial evaluation of a polycationic calix[4]arene derivative alone and in combination with antibiotics

Published:2018 Issue:1 Volume:9 Page:160-164
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Consoli G. M. L.¹²³⁴^ORCID,Granata G.¹²³⁴^ORCID,Picciotto R.⁵⁶⁷⁴,Blanco A. R.⁸⁹⁴,Geraci C.¹²³⁴^ORCID,Marino A.¹⁰¹¹¹²⁴^ORCID,Nostro A.¹⁰¹¹¹²⁴^ORCID

Affiliation:

1. Institute of Biomolecular Chemistry

2. National Research Council (C.N.R.)

3. 95126 Catania

4. Italy

5. Laboratory of Photochemistry

6. Department of Drug Science

7. 95125 Catania

8. Alfa Intes ITS S.r.l.

9. 80026 Napoli

10. Department of Chemical, Biological, Pharmaceutical and Environmental Sciences

11. University of Messina

12. Messina 98168

Abstract

Synthesis of a new polycationic calix[4]arene derivative: intrinsic antibacterial activity and additive effect when combined with antibiotics against ATCC and resistant bacteria.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MD/C7MD00527J

Reference27 articles.

1. Reviving old antibiotics

2. P. Neri , J. L.Sessler and M.-X.Wang , Calixarenes and Beyond , Springer , Berlin-Heidelberg , 2016

3. Toxicity and biodistribution of para-sulfonato-calix[4]arene in mice

4. Applications of calixarene nano-baskets in pharmacology

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