The chemopreventive effects of Huangqin-tea against AOM-induced preneoplastic colonic aberrant crypt foci in rats and omics analysis-Reference-Cited by-同舟云学术

The chemopreventive effects of Huangqin-tea against AOM-induced preneoplastic colonic aberrant crypt foci in rats and omics analysis

Published:2020 Issue:11 Volume:11 Page:9634-9650
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Shen Jie¹²³⁴⁵,Li Pei¹²³⁴⁵^ORCID,Liu Shuangshuang¹²³⁴⁵,Liu Qing¹²³⁴⁵,Li Yue¹²³⁴⁵^ORCID,Zhang Zheng¹²³⁴⁵,Yang Chengmin¹²³⁴⁵,Hu Mengying⁶⁷⁵,Sun Yuhua⁶⁷⁵,He Chunnian¹²³⁴⁵^ORCID,Xiao Peigen¹²³⁴⁵

Affiliation:

1. Institute of Medicinal Plant Development

2. Chinese Academy of Medical Science

3. Peking Union Medical College

4. Beijing 100193

5. China

6. Xinjiang Institute of Materia Medica

7. Urumqi 830004

Abstract

In the AOM-induced precancerous colorectal lesions rat model, HQT inhibits aberrant crypt foci formation mainly by modulating the gut microbiota composition and improving metabolomic disorders.

Funder

National Major Science and Technology Projects of China

Chinese Academy of Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/FO/D0FO01731K

Reference75 articles.

1. Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer

2. Aberrant crypt foci as precursors in colorectal cancer progression