A highly efficient and eco-friendly method for the synthesis of 1,3-indandione ring-fused 3-oxindoles bearing two contiguous quaternary stereocenters via an aldol reaction in aqueous media

Author:

Liu Xiong-Li12345,Pan Bo-Wen12345,Zhang Wen-Hui12345,Yang Chao12345,Yang Jun12345,Shi Yang12345,Feng Ting-Ting12345,Zhou Ying12345,Yuan Wei-Cheng67895

Affiliation:

1. Guizhou Engineering Center for Innovative Traditional Chinese Medicine and Ethnic Medicine

2. College of Pharmacy

3. Guizhou University

4. Guiyang

5. China

6. Key Laboratory for Asymmetric Synthesis & Chirotechnology of Sichuan Province

7. Chengdu Institute of Organic Chemistry

8. Chinese Academy of Sciences

9. Chengdu 610041

Abstract

The synthesis and antitumor activity evaluation of 1,3-indandione ring-fused 3-oxindoles.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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