Fc microparticles can modulate the physical extent and magnitude of complement activity

Author:

Holt Brandon Alexander12345ORCID,Bellavia Michael C.12345,Potter Daniel45236,White David7893,Stowell Sean R.10111223,Sulchek Todd12365

Affiliation:

1. Wallace H. Coulter Department of Biomedical Engineering at the Georgia Institute of Technology and Emory University

2. Atlanta

3. USA

4. The Parker H. Petit Institute for Bioengineering and Bioscience

5. Georgia Institute of Technology

6. The G. W. Woodruff School of Mechanical Engineering

7. United States Department of Agriculture

8. National Centers for Animal Health

9. Ames

10. Center for Transfusion and Cellular Therapies

11. Department of Pathology and Laboratory Medicine

12. Emory University School of Medicine

Abstract

Biomaterials that exploit Fc presentation will provide new possibilities to functionally modulate complement activation to achieve a desired clinical result.

Funder

Division of Materials Research

National Institute of Biomedical Imaging and Bioengineering

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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