Newly synthesized 3-(4-chloro-phenyl)-3-hydroxy-2,2-dimethyl-propionic acid methyl ester derivatives selectively inhibit the proliferation of colon cancer cells-Reference-Cited by-同舟云学术

Newly synthesized 3-(4-chloro-phenyl)-3-hydroxy-2,2-dimethyl-propionic acid methyl ester derivatives selectively inhibit the proliferation of colon cancer cells

Published:2020 Issue:15 Volume:10 Page:8825-8841
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

El Rayes Samir M.¹²³⁴⁵^ORCID,Aboelmagd Ahmed¹²³⁴⁵^ORCID,Gomaa Mohamed S.⁶⁷⁸⁹¹⁰,Fathalla Walid¹¹¹²¹³¹⁴⁵^ORCID,Ali Ibrahim A. I.¹²³⁴⁵,Pottoo Faheem H.¹⁵⁷⁸⁹¹⁰,Khan Firdos Alam¹⁶¹⁷⁸⁹¹⁸^ORCID

Affiliation:

1. Department of Chemistry

2. Faculty of Science

3. Suez Canal University

4. Ismailia

5. Egypt

6. Department of Pharmaceutical

7. College of Clinical Pharmacy

8. Imam Abdulrahman Bin Faisal University

9. Dammam 31441

10. Kingdom of Saudi Arabia

11. Department of Physics and Math.

12. Faculty of Engineering

13. Port-Said University

14. Port-Said

15. Department of Pharmacology

16. Department of Stem Cell Research

17. Institute of Research and Medical Consultations (IRMC)

18. Saudi Arabia

Abstract

A series of 24 compounds were synthesized based on structure modification of the model methyl-3-(4-chlorophenyl)-3-hydroxy-2,2-dimethylpropanoate as potent HDACIs.

Funder

Science and Technology Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/C9RA10950A

Reference39 articles.

1. H. P.Rang and M. M.Dale , ELBS With Churchill Livingstone Pharmacology, Cancer Chemotherapy Chapter , 2nd edn, 1994 , p. 781

2. Global cancer statistics

3. An assessment of GLOBOCAN methods for deriving national estimates of cancer incidence