Acyclonucleosides bearing coplanar arylethynyltriazole nucleobases: synthesis, structural analysis, and biological evaluation-Reference-Cited by-同舟云学术

Acyclonucleosides bearing coplanar arylethynyltriazole nucleobases: synthesis, structural analysis, and biological evaluation

Published:2017 Issue:16 Volume:41 Page:8509-8519
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Chen Mimi¹²³⁴⁵,Zhou Zhengwei¹²³⁴⁵,Suo Yaxiong¹²³⁴⁵,Li Mengyao¹²³⁴⁵,Yao Jianhua⁶⁷⁸⁵^ORCID,Peng Ling⁹¹⁰¹¹¹²¹³^ORCID,Xia Yi¹²³⁴⁵^ORCID

Affiliation:

1. Chongqing Key Laboratory of Natural Product Synthesis and Drug Research

2. School of Pharmaceutical Sciences

3. Chongqing University

4. Chongqing

5. China

6. Shanghai Institute of Organic Chemistry

7. Chinese Academy of Sciences

8. Shanghai

9. Aix-Marseille Université

10. CNRS

11. Centre Interdisciplinaire de Nanoscience de Marseille

12. UMR 7325

13. Equipe Labellisées Ligue Contre le Cancer

Abstract

The efficient synthesis of acyclonucleosides bearing coplanar 3-arylethynyltriazole motifs was established and several compounds displayed antiproliferative activity against cancer cells.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2017/NJ/C7NJ01406F

Reference46 articles.

1. C. Simons , Nucleoside mimetics: their chemistry and biological properties., Gordon and Breach Science Publishers, Amsterdam, 2001

2. Nucleoside analogs: molecular mechanisms signaling cell death

3. Nucleoside/Nucleotide Analogue Polymerase Inhibitors in Development

4. Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases

5. Metabolism, Biochemical Actions, and Chemical Synthesis of Anticancer Nucleosides, Nucleotides, and Base Analogs

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthesis of Substituted 1,2,4-Triazole-3-Thione Nucleosides Using E. coli Purine Nucleoside Phosphorylase;Biomolecules;2024-06-24

2. Electrochemical Cyclization of α,β‐Alkynic Hydrazones and Primary Amines for the Synthesis of 3‐Alkynyltriazoles;Asian Journal of Organic Chemistry;2023-10-11

3. Chemo-enzymatic synthesis of 5-substituted ribavirin analogs: Unexpected cooperative effect in the interaction of 5-alkyloxymethyl 1,2,4-triazol-3-carboxamides with E. coli purine nucleoside phosphorylase active site;Sustainable Chemistry and Pharmacy;2022-12

4. Synthesis of ribavirin 1,2,3- and 1,2,4-triazolyl analogs with changes at the amide and cytotoxicity in breast cancer cell lines;Nucleosides, Nucleotides & Nucleic Acids;2022-08-05

5. 1,2,4-Triazoles;Comprehensive Heterocyclic Chemistry IV;2022