A self-assembling nanoparticle vaccine targeting the conserved epitope of influenza virus hemagglutinin stem elicits a cross-protective immune response-Reference-Cited by-同舟云学术

A self-assembling nanoparticle vaccine targeting the conserved epitope of influenza virus hemagglutinin stem elicits a cross-protective immune response

Published:2022 Issue:8 Volume:14 Page:3250-3260
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Qiao Yongbo¹,Li Shuang¹,Jin Shenghui¹,Pan Yi¹,Shi Yuhua¹,Kong Wei¹²,Shan Yaming¹²^ORCID

Affiliation:

1. National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, Jilin 130012, China

2. Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life Sciences, Jilin University, Changchun, Jilin 130012, China

Abstract

A schematic overview showing nanoparticle preparation, BALB/c mice immunization, and viral challenge. Humoral and cellular immune responses were determined after three immunizations, and protective effects were evaluated after the challenge.

Funder

National Natural Science Foundation of China

Department of Science and Technology of Jilin Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NR/D1NR08460G

Reference41 articles.

1. Seasonality of coronaviruses and other respiratory viruses in Canada: Implications for COVID-19

2. Influenza vaccination strategies targeting the hemagglutinin stem region