AIEgen-based theranostic system: targeted imaging of cancer cells and adjuvant amplification of antitumor efficacy of paclitaxel

Author:

Chen Chao12345,Song Zhegang678910,Zheng Xiaoyan678910,He Zikai678910,Liu Bin111213,Huang Xuhui678910,Kong Deling12345,Ding Dan12345,Tang Ben Zhong678910ORCID

Affiliation:

1. Key Laboratory of Bioactive Materials

2. Ministry of Education

3. State Key Laboratory of Medicinal Chemical Biology

4. College of Life Sciences

5. Nankai University

6. Department of Chemistry

7. Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction

8. Division of Biomedical Engineering

9. The Hong Kong University of Science & Technology (HKUST)

10. China

11. Department of Chemical and Biomolecular Engineering

12. National University of Singapore

13. Singapore 117585

Abstract

An AIEgen-based theranostic system is developed to amplify the antitumor efficacy of paclitaxel with a synergistic effect of “0 + 1 > 1”.

Funder

National Research Foundation Singapore

National Natural Science Foundation of China

Innovation and Technology Commission

National University of Singapore

University Grants Committee

Research Grants Council, University Grants Committee

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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