A sialic acid-targeted near-infrared theranostic for signal activation based intraoperative tumor ablation

Author:

Wu Xuanjun12345,Yu Mingzhu12345,Lin Bijuan12345,Xing Hongjie12345,Han Jiahuai678910,Han Shoufa12345

Affiliation:

1. Department of Chemical Biology

2. College of Chemistry and Chemical Engineering

3. the Key Laboratory for Chemical Biology of Fujian Province

4. The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation

5. and Innovation Center for Cell Biology

6. State Key Laboratory of Cellular Stress Biology

7. Innovation Center for Cell Biology

8. School of Life Sciences

9. Xiamen University

10. Xiamen

Abstract

A sialic acid-targeted near-infrared profluorophore with pH-responsive fluorescence and photothermal properties was developed for fluorescence-guided staging and photothermal therapy of viable tumors exposed during surgery.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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