Synthesis, characterization and biological evaluation of six highly cytotoxic ruthenium(ii) complexes with 4′-substituted-2,2′:6′,2′′-terpyridine-Reference-Cited by-同舟云学术

Synthesis, characterization and biological evaluation of six highly cytotoxic ruthenium(ii) complexes with 4′-substituted-2,2′:6′,2′′-terpyridine

Author:

Qin Qi-Pin¹²³⁴⁵^ORCID,Meng Ting¹²³⁴⁵,Tan Ming-Xiong¹²³⁴⁵^ORCID,Liu Yan-Cheng⁶⁷⁸⁹⁵^ORCID,Wang Shu-Long¹²³⁴⁵,Zou Bi-Qun¹⁰¹¹¹²⁵^ORCID,Liang Hong⁶⁷⁸⁹⁵

Affiliation:

1. Guangxi Key Laboratory of Agricultural Resources Chemistry and Biotechnology

2. College of Chemistry and Food Science

3. Yulin Normal University

4. Yulin 537000

5. PR China

6. State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources

7. School of Chemistry and Pharmacy

8. Guangxi Normal University

9. Guilin 541004

10. Department of Chemistry

11. Guilin Normal College

12. Gulin 541001

Abstract

Various experiments show that Ru1 and Ru6 are telomerase inhibitors targeting c-myc G4 DNA and also cause apoptosis of Hep-G2 cells.

Funder

National Natural Science Foundation of China

Ministry of Science and Technology of the People's Republic of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

Reference77 articles.

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