Structure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit Promoter
Author:
Affiliation:
1. Contribution from the Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, and Cancer Research UK Biomolecular Structure Group, School of Pharmacy, University of London, London WC1N 1AX, United Kingdom
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja068739h
Reference43 articles.
1. Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.
2. A loss-of-function mutation of c-kit results in depletion of mast cells and interstitial cells of Cajal, while its gain-of-function mutation results in their oncogenesis
3. Activating c-kit Gene Mutations in Human Germ Cell Tumors
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