A protecting group-free synthesis of (−)-hortonones A–C from the Inhoffen–Lythgoe diol-Reference-Cited by-同舟云学术

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A protecting group-free synthesis of (−)-hortonones A–C from the Inhoffen–Lythgoe diol

Published:2016 Issue:37 Volume:14 Page:8728-8731
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Stambulyan Hovsep¹²³⁴,Minehan Thomas G.¹²³⁴

Affiliation:

1. Department of Chemistry and Biochemistry

2. California State University

3. Northridge

4. USA

Abstract

Synthesis of (−)-hortonones A–C from vitamin D₂ reveals that the natural products are of opposite absolute configuration to originally proposed.

Funder

American Chemical Society Petroleum Research Fund

Division of Chemistry

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB01738J

Reference33 articles.

1. Hortonones A to C, Hydroazulenones from the Genus Hortonia

2. Analogues of the Inhoffen–Lythgoe diol with anti-proliferative activity

3. Efficient and scalable total synthesis of calcitroic acid and its 13C-labeled derivative

4. Design, synthesis, and evaluation of hybrid vitamin D3 side chain analogues as hedgehog pathway inhibitors

5. Vitamin D receptor agonist/histone deacetylase inhibitor molecular hybrids

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