A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions
Author:
Affiliation:
1. Department of Process Research & Development
2. Merck & Co., Inc.
3. Rahway
4. USA
Abstract
Detailed mechanistic studies of a Pd-catalyzed asymmetric C–N coupling led to a rational design of a new series of bis-phosphine mono-oxides ligated Pd(ii) pre-catalysts that allow for reliable and complete catalyst activation.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/SC/C6SC05472B
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