Highly efficient ruthenium-catalyzed asymmetric hydrogenation of N-heteroaryl vinyl ethers-Reference-Cited by-同舟云学术

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Highly efficient ruthenium-catalyzed asymmetric hydrogenation of N-heteroaryl vinyl ethers

Published:2022 Issue:11 Volume:9 Page:3022-3026
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Feng Song¹^ORCID,Ren Baoqi¹,Li Lige¹,Xia Fengmin²,Tang Zhiyong²,Zhang Yu³,Liu Xiaoning³,Lu Qixuan³,Zhong Wenge¹

Affiliation:

1. Regor Therapeutics Group, 1206 Zhangjiang Road, Building C, Pu Dong New District, Shanghai, 201210, China

2. Pharmaron Beijing Co., Ltd, 6 Taihe Road, BDA, Beijing, 100176, China

3. BioDuro-Sundia, 388 Jialilue Road, Shanghai, Zhangjiang Hi-tech Park, Shanghai, 201203, China

Abstract

N-directing asymmetric hydrogenation of vinyl ether can afford excellent yield and ee without a coordinating group engagement.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D2QO00448H

Reference24 articles.

1. Synthesis of deuterium-labeled crizotinib, a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK)

2. Design, synthesis and biological evaluations of 2-amino-4-(1-piperidine) pyridine derivatives as novel anti crizotinib-resistant ALK/ROS1 dual inhibitors

3. U.S. FDA Approved Drugs from 2015–June 2020: A Perspective

4. New drug approvals for 2019: Synthesis and clinical applications

5. Where Do Recent Small Molecule Clinical Development Candidates Come From?

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1. Unlocking the Asymmetric Hydrogenation of Tetrasubstituted Acyclic Enones;Angewandte Chemie International Edition;2023-12-28

2. Unlocking the Asymmetric Hydrogenation of Tetrasubstituted Acyclic Enones;Angewandte Chemie;2023-12-28

3. Direct Construction of Chiral Ether via Highly Efficient Heck Reaction and N-Directed Asymmetric Hydrogenation for Large-Scale Synthesis of MALT1 Inhibitor RGT-068A;Organic Process Research & Development;2022-11-03

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