Multifunctional nanomicelles constructedviaan aggregation and de-aggregation strategy for magnetic resonance/NIR II fluorescence imaging-guided type I photodynamic therapy

Author:

Wang Lirong12,Qi Ji3ORCID,Zhang Ke4ORCID,Zhuang Zeyan12,Ding Keke5,Chen Xu12,Shan Hong4,Ding Dan3ORCID,Qin Anjun12ORCID,Tang Ben Zhong267

Affiliation:

1. State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, South China University of Technology, Guangzhou 510640, China

2. Center for Aggregation-Induced Emission, AIE Institute, South China University of Technology, Guangzhou 510640, China

3. State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin 300071, China

4. Center for Interventional Medicine, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China

5. Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China

6. School of Science and Engineering, Shenzhen Institute of Aggregate Science and Engineering, The Chinese University of Hong Kong, Shenzhen, 518172, Guangdong, China

7. Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration and Reconstruction, The Hong Kong University of Science & Technology, Clear Water Bay, Kowloon, Hong Kong, China

Abstract

This work demonstrated that the aggregation and de-aggregation strategy of AIEgens in nanomicelles is very attractive for constructing multifunctional theranostic probes.

Funder

Natural Science Foundation of Guangdong Province

National Natural Science Foundation of China

National Key Research and Development Program of China

Innovation and Technology Commission

State Key Laboratory of Luminescent Materials and Devices

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Materials Science

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