A green and facile method for the preparation of a pH-responsive alginate nanogel for subcellular delivery of doxorubicin
Author:
Affiliation:
1. Key Laboratory for Green Chemical Process of Ministry of Education
2. Hubei Key Laboratory for Novel Reactor and Green Chemistry Technology
3. School of Chemical Engineering and Pharmacy
4. Wuhan Institute of Technology
5. Wuhan 430073
Abstract
A one-pot preparation of a drug-loaded alginate nanogel was achieved upon the optimization of the concentration and their ratio of alginate, calcium ion and doxorubicin. The nanogel exhibited apparent pH-responsive release and subcellular delivery.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA13313K
Reference27 articles.
1. Self-Assembly of Thermally Responsive Nanoparticles of a Genetically Encoded Peptide Polymer by Drug Conjugation
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