N,N-Dialkylbenzimidazol-2-ylidene platinum complexes – effects of alkyl residues and ancillary cis-ligands on anticancer activity-Reference-Cited by-同舟云学术

N,N-Dialkylbenzimidazol-2-ylidene platinum complexes – effects of alkyl residues and ancillary cis-ligands on anticancer activity

Published:2018 Issue:48 Volume:47 Page:17367-17381
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Rehm Tobias¹²³⁴,Rothemund Matthias¹²³⁴,Bär Alexander¹²³⁴,Dietel Thomas⁵²³⁴^ORCID,Kempe Rhett⁵²³⁴,Kostrhunova Hana⁶⁷⁸⁹^ORCID,Brabec Viktor⁶⁷⁸⁹^ORCID,Kasparkova Jana⁶⁷⁸⁹^ORCID,Schobert Rainer¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University Bayreuth

3. 95440 Bayreuth

4. Germany

5. Lehrstuhl fuer Anorganische Chemie II

6. Institute of Biophysics

7. Academy of Sciences of the Czech Republic

8. CZ-61265 Brno

9. Czech Republic

Abstract

Benzimidazol-2-ylidene platinum complexes exhibit anticancer activity, which is tuneable via N-alkyl residues and ancillary ligands and is different from that of cisplatin.

Funder

Deutsche Forschungsgemeinschaft

Grantová Agentura České Republiky

European Cooperation in Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/DT/C8DT03360A

Reference52 articles.

1. Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects