Identification of readily available pseudo-natural products-Reference-Cited by-同舟云学术

Identification of readily available pseudo-natural products

Published:2024 Issue:8 Volume:15 Page:2709-2717
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Pahl Axel¹^ORCID,Grygorenko Oleksandr O.²³^ORCID,Kondratov Ivan S.²⁴⁵,Waldmann Herbert⁶⁷^ORCID

Affiliation:

1. Compound Management and Screening Center (COMAS), Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany

2. Enamine Ltd., Chervonotkatska Street 78, Kyïv 02094, Ukraine

3. Taras Shevchenko National University of Kyiv, Volodymyrska Street 60, Kyïv 01601, Ukraine

4. V.P. Kukhar Institute of Bioorganic Chemistry & Petrochemistry, NAS of Ukraine, Akademik Kukhar Street 1, Kyïv 02660, Ukraine

5. Enamine Germany GmbH, Industriepark Hoechst, G837, 65926 Frankfurt am Main, Germany

6. Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany

7. Faculty of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn-Strasse 6, 44221 Dortmund, Germany

Abstract

Pseudo-natural products (PNPs) combine fragments derived from NPs in ways that are not found in nature, and may lead to the discovery of novel chemotypes for unexpected targets or the identification of unprecedented bioactivities.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MD/D4MD00310A

Reference41 articles.

1. Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

2. Pseudo-natural products and natural product-inspired methods in chemical biology and drug discovery

3. The Symbiotic Relationship Between Drug Discovery and Organic Chemistry

4. Molecular diversity by design

5. Re-engineering natural products to engage new biological targets

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