Poly(ethylene glycol) modified Mn2+ complexes as contrast agents with a prolonged observation window in rat MRA-Reference-Cited by-同舟云学术

Poly(ethylene glycol) modified Mn2+ complexes as contrast agents with a prolonged observation window in rat MRA

Published:2017 Issue:86 Volume:7 Page:54603-54609
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wu Changqiang¹²³⁴⁵^ORCID,Yang Li¹²³⁴,Chen Zhuzhong⁶⁷³⁴,Zhang Houbing¹²³⁴,Li Danyang¹²³⁴,Lin Bingbing¹²³⁴,Zhu Jiang⁵⁸⁹¹⁰⁴,Ai Hua¹²³⁴¹¹,Zhang Xiaoming⁵¹²⁹¹⁰⁴

Affiliation:

1. National Engineering Research Center for Biomaterials

2. Sichuan University

3. Chengdu 610064

4. P. R. China

5. Sichuan Key Laboratory of Medical Imaging

6. PET/CT of Imaging Department

7. Sichuan Cancer Hospital

8. Department of Chemistry

9. North Sichuan Medical College

10. Nanchong 637000

11. Department of Radiology

12. School of Medical Imaging

Abstract

PEGylated Mn²⁺ complexes show higher relaxivity and longer blood circulation time than free Mn²⁺ complexes.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA09975D

Reference33 articles.

1. Manganese Based MR Contrast Agents: Formulation and Clinical Applications

2. Manganese-based MRI contrast agents: past, present, and future

3. Mn2+ Complexes with 12-Membered Pyridine Based Macrocycles Bearing Carboxylate or Phosphonate Pendant Arm: Crystallographic, Thermodynamic, Kinetic, Redox, and 1H/17O Relaxation Studies

4. Gadolinium-based contrast agents and NSF: Evidence from animal experience

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