Ultra-small manganese dioxide nanoparticles with high T1 relaxivity for magnetic resonance angiography

Author:

Jiang Yuting1,Gu Haojie1,Cai Zhongyuan1,Fu Shengxiang2,Cao Yingzi1,Jiang Lingling1,Wu Changqiang3ORCID,Chen Wei3,Xia Chunchao2,Lui Su2,Song Bin2,Gong Qiyong45,Ai Hua12ORCID

Affiliation:

1. National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610065, China

2. Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China

3. Medical Imaging Key Laboratory of Sichuan Province and School of Medical Imaging, North Sichuan Medical College, Nanchong, 637000, China

4. Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, Chengdu, 610041, China

5. Psychoradiology Research Unit of Chinese Academy of Medical Sciences, Sichuan University, Chengdu, 610041, China

Abstract

Ultra-small MnO2/PAA NPs with a high relaxivity of 29.0 Mn mM−1 s−1 are promising candidates for MR imaging of vascular pathologies.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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