Quercetin and its metabolites inhibit the membrane NADPH oxidase activity in vascular smooth muscle cells from normotensive and spontaneously hypertensive rats-Reference-Cited by-同舟云学术

Quercetin and its metabolites inhibit the membrane NADPH oxidase activity in vascular smooth muscle cells from normotensive and spontaneously hypertensive rats

Published:2015 Issue:2 Volume:6 Page:409-414
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Jimenez R.¹²³⁴,Lopez-Sepulveda R.¹²³⁴,Romero M.¹²³⁴,Toral M.¹²³⁴,Cogolludo A.¹⁵⁶⁷⁸,Perez-Vizcaino F.¹⁵⁶⁷⁸,Duarte J.¹²³⁴

Affiliation:

1. Department of Pharmacology

2. School of Pharmacy

3. University of Granada

4. Spain

5. School of Medicine

6. University Complutense of Madrid

7. Ciber Enfermedades Respiratorias (Ciberes) and Instituto de Investigación Sanitaria Gregorio Marañón (IISGM)

8. Madrid

Abstract

Quercetin, the most abundant dietary flavonol, exerts antioxidant effects reducing vascular superoxide (O₂⁻) and improving endothelial function in animal models of cardiovascular disease.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2015/FO/C4FO00818A

Reference40 articles.

1. Oxidative Stress and Pathological Changes After Coronary Artery Interventions

2. Vascular NADPH oxidases as drug targets for novel antioxidant strategies

3. NAD(P)H Oxidase

4. NADPH oxidase, superoxide overproduction and nitric oxide bioavailability in essential hypertension

5. Increased NADPH oxidase activity mediates spontaneous aortic tone in genetically hypertensive rats

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