Biomechanical studies on biomaterial degradation and co-cultured cells: mechanisms, potential applications, challenges and prospects

Author:

Wang Lu12345,Wu Shuai12345,Cao Guangxiu12345,Fan Yubo12345,Dunne Nicholas678910,Li Xiaoming12345ORCID

Affiliation:

1. Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education

2. School of Biological Science and Medical Engineering

3. Beihang University

4. Beijing 100083

5. China

6. Centre for Medical Engineering Research

7. School of Mechanical and Manufacturing Engineering

8. Dublin City University

9. Dublin 9

10. Ireland

Abstract

This review provides a comprehensive overview of biomechanical studies on biomaterial degradation and co-cultured cells as well as valuable biomechanical ideas on how to design or optimize cell biomaterial co-culture system.

Funder

National Natural Science Foundation of China

National Basic Research Program of China

Fok Ying Tung Education Foundation

State Key Laboratory of New Ceramics and Fine Processing

Tsinghua University

Ministry of Science and Technology of the People's Republic of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Reference190 articles.

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2. Immunomodulatory polymeric scaffold enhances extracellular matrix production in cell co-cultures under dynamic mechanical stimulation

3. Biodegradation and bioresorption of calcium phosphate ceramics

4. O. M. Goudouri , P.Balasubramanian and A. R.Boccaccini , Characterizing the degradation behavior of bioceramic scaffolds , Characterisation and Design of Tissue Scaffolds , 2016 , pp. 127–147

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