Pyrrolizidine alkaloids: occurrence, biology, and chemical synthesis-Reference-Cited by-同舟云学术

Pyrrolizidine alkaloids: occurrence, biology, and chemical synthesis

Published:2017 Issue:1 Volume:34 Page:62-89
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Robertson Jeremy¹²³⁴⁵^ORCID,Stevens Kiri¹²³⁴⁵

Affiliation:

1. Department of Chemistry

2. Chemistry Research Laboratory

3. University of Oxford

4. Oxford

5. UK

Abstract

This review focuses on the isolation, biological activity, metabolism, and (bio)synthesis of natural products containing a 1-azabicyclo[3.3.0]octane core (January 2013 to December 2015).

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/NP/C5NP00076A

Reference136 articles.

1. Pyrrolizidine alkaloids

2. In Silico Prediction of the Site of Oxidation by Cytochrome P450 3A4 That Leads to the Formation of the Toxic Metabolites of Pyrrolizidine Alkaloids

3. Species-Specific Differences in the in Vitro Metabolism of Lasiocarpine

4. Pyrrolizidine Alkaloid-Derived DNA Adducts as a Common Biological Biomarker of Pyrrolizidine Alkaloid-Induced Tumorigenicity

5. Reaction of Dehydropyrrolizidine Alkaloids with Valine and Hemoglobin

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