Synthesis of 4-substituted pyrazole-3,5-diamines via Suzuki–Miyaura coupling and iron-catalyzed reduction-Reference-Cited by-同舟云学术

Synthesis of 4-substituted pyrazole-3,5-diamines via Suzuki–Miyaura coupling and iron-catalyzed reduction

Published:2017 Issue:48 Volume:15 Page:10200-10211
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Tomanová Monika¹²³⁴⁵^ORCID,Jedinák Lukáš⁶⁷³⁸⁵^ORCID,Košař Jan⁶⁷³⁸⁵,Kvapil Lubomír⁶⁷³⁸⁵,Hradil Pavel⁶⁷³⁸⁵,Cankař Petr⁶⁷³⁸⁵^ORCID

Affiliation:

1. Institute of Molecular and Translation Medicine

2. Faculty of Medicine

3. Palacký University

4. 77900 Olomouc

5. Czech Republic

6. Department of Organic Chemistry

7. Faculty of Science

8. 77146 Olomouc

Abstract

A general and efficient synthesis of 4-substituted-1H-pyrazole-3,5-diamines was developed to access derivatives with an aryl, heteroaryl, or styryl group, which are otherwise relatively difficult to prepare.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB02373A

Reference44 articles.

1. Synthesis, antimicrobial and antioxidant activities of substituted pyrazoles, isoxazoles, pyrimidine and thioxopyrimidine derivatives

2. Anti-coxsackievirus B3 activity of 2-amino-3-nitropyrazolo[1,5-a]pyrimidines and their analogs

3. Pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors. Synthesis and SAR of 2-substituted 4-methyl-8-(morpholine-4-sulfonyl)-pyrrolo[3,4-c]quinoline-1,3-diones

4. 2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2

5. Cyclin-Dependent Kinase Pathways As Targets for Cancer Treatment

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Polynitro-functionalized 4-phenyl-1H-pyrazoles as heat-resistant explosives;Organic & Biomolecular Chemistry;2023

2. Synthesis and Structural Optimization of 2,7,9-Trisubstituted purin-8-ones as FLT3-ITD Inhibitors;International Journal of Molecular Sciences;2022-12-18

3. Synthesis and structural optimization of 2,7,9-trisubstituted purin-8-ones as FLT3-ITD inhibitors;2022-12-11

4. Alkyl-Substituted N,S-Embedded Heterocycloarenes with a Planar Aromatic Configuration for Hosting Fullerenes and Organic Field-Effect Transistors;Journal of the American Chemical Society;2022-11-07

5. Connecting Energetic Nitropyrazole and Nitrobenzene Moieties with C−C Bonds using Suzuki Cross‐Coupling Reaction: A Novel Route to Thermally Stable Energetic Materials;Asian Journal of Organic Chemistry;2022-10-25