Oligosaccharides derived from <i>Lycium barbarum</i> ameliorate glycolipid metabolism and modulate the gut microbiota community and the faecal metabolites in a type 2 diabetes mouse model: metabolomic bioinformatic analysis-Reference-Cited by-同舟云学术

Oligosaccharides derived from Lycium barbarum ameliorate glycolipid metabolism and modulate the gut microbiota community and the faecal metabolites in a type 2 diabetes mouse model: metabolomic bioinformatic analysis

Published:2022 Issue:9 Volume:13 Page:5416-5429
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Liu Hao¹²,Zhang Zheng¹²,Li Jianpeng¹²,Liu Wei³,Warda Mohamad⁴,Cui Bo¹²^ORCID,Abd El-Aty A. M.¹⁵⁶^ORCID

Affiliation:

1. State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Sciences, Jinan, 250353, China

2. School of Food Science and Engineering, Qilu University of Technology, Shandong Academy of Sciences, Jinan, Shandong, 250353, China

3. Yucheng People's Hospital, Dezhou, 251200, China

4. Department of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Cairo University, Giza-12211, Egypt

5. Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza-12211, Egypt

6. Department of Medical Pharmacology, Medical Faculty, Ataturk University, Erzurum 25240, Turkey

Abstract

This study investigated how Lycium barbarum oligosaccharides improve glycolipid metabolism and modulate the gut microbial community and faecal metabolites in a mouse model of type 2 diabetes.

Funder

National Key Research and Development Program of China

Natural Science Foundation of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D1FO02667D

Reference84 articles.

1. Unravelling the involvement of gut microbiota in type 2 diabetes mellitus

2. A murine model of type 2 diabetes mellitus developed using a combination of high fat diet and multiple low doses of streptozotocin treatment mimics the metabolic characteristics of type 2 diabetes mellitus in humans

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