Self-assembly of a fluorescent virus-like particle for imaging in tissues with high autofluorescence-Reference-Cited by-同舟云学术

Self-assembly of a fluorescent virus-like particle for imaging in tissues with high autofluorescence

Published:2023 Issue:20 Volume:11 Page:4445-4452
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Trashi Ikeda¹,Durbacz Mateusz Z.²,Trashi Orikeda¹,Wijesundara Yalini H.¹,Ehrman Ryanne N.¹,Chiev Alyssa C.¹,Darwin Cary B.¹,Herbert Fabian C.¹,Gadhvi Jashkaran³^ORCID,De Nisco Nicole J.³,Nielsen Steven O.¹^ORCID,Gassensmith Jeremiah J.¹⁴^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, The University of Texas at Dallas, Richardson, Texas 75080, USA

2. Department of Molecular Biology and Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA

3. Department of Biological Science, The University of Texas at Dallas, Richardson, Texas 75080, USA

4. Department of Bioengineering, The University of Texas at Dallas, Richardson, Texas 75080, USA

Abstract

Qβ VLP simplified assembly approach uses the positively charged Rev tag to interact electrostatically with the negatively charged RNAs. This system exploits the known hairpins produced in the coat protein sequence to template the assembly of the full viral capsid.

Funder

National Science Foundation

Welch Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D3TB00469D

Reference58 articles.

1. Construction and Characterization of Virus-Like Particles: A Review

2. Efficient disulfide bond formation in virus-like particles

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5. Real-Time Assembly of Viruslike Nucleocapsids Elucidated at the Single-Particle Level

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