An efficient approach to gem-difluorocyclopropylstannanes via highly regio- and stereoselective hydrostannylation of gem-difluorocyclopropenes and their unique ring-opening reaction to afford β-fluoroallylic alcohols-Reference-Cited by-同舟云学术

An efficient approach to gem-difluorocyclopropylstannanes via highly regio- and stereoselective hydrostannylation of gem-difluorocyclopropenes and their unique ring-opening reaction to afford β-fluoroallylic alcohols

Published:2015 Issue:12 Volume:13 Page:3721-3731
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Nihei T.¹²³⁴,Hoshino T.¹²³⁴,Konno T.¹²³⁴

Affiliation:

1. Department of Chemistry and Materials Technology

2. Kyoto Institute of Technology

3. Kyoto

4. 606-8585 Japan

Abstract

gem-Difluorocyclopropylstannanes, prepared via the hydrostannylation of gem-difluorocyclopropenes, were treated with MeLi and then quenching agents, to give (Z)-β-fluoroallyllic alcohols, ethers, esters, and amides.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB00046G

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3. The synthesis of methoxy and keto mycolic acids containing methyl-trans-cyclopropanes

4. Synthesis of the Otteliones A and B: Use of a Cyclopropyl Group as Both a Steric Shield and a Vinyl Equivalent

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